>>165148, >>165153, >>165161, >>165196 pb

Microbiota–Gut–Brain Axis and Epilepsy: A Review on Mechanisms and Potential Therapeutics

"The microbiota–gut–brain axis in epilepsy. Bad gut microbiota could upregulate the production of epilepsy-promoting metabolites, the secretion of inflammatory factors, and so on, which lead to abnormal GABA/glutamate ratio and then induce the epilepsy. Chronic stress may be a trigger for this process. Healthy gut microbiota could produce good metabolites, such as SCFAs and serotonin, which could inhibit the occurrence of epilepsy. HPA axis, enteric nervous system, and vagus nervous system are also involved in the interaction between gut microbiota and epilepsy."

https://pmc.ncbi.nlm.nih.gov/articles/PMC8542678/